"Multiple Sclerosis, Diabetes, Parkinson's and Alzheimer's are not diseases. They are reactions to disease." Over the past two decades, I have studied fat embolism and related mechanisms of tissue injury. Through this work, I have developed a hypothesis that challenges traditional views of plaque formation and the body's response to injury. This proposed model suggests that plaque formation is not simply a metabolic consequence of elevated cholesterol, but rather a reactive b